• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文OA文献 >Poor Physical Performance Predicts Future Onset of Depression in Elderly People:\ud Pro.V.A. Longitudinal Study
【2h】

Poor Physical Performance Predicts Future Onset of Depression in Elderly People:\ud Pro.V.A. Longitudinal Study

机译：身体表现不佳预示着老年人抑郁症的发作：\ ud Pro.V.A.纵向研究

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Reduced physical performance is predictive of deleterious outcomes in older adults. Data considering objective physical performance and incident depression is sparse. Objective: We investigated whether objective physical performance can predict incident depression among non-depressed older adults during a 4-year study. Design: longitudinal. Methods: From 3,099 older individuals initially enrolled in the Progetto Veneto Anziani study, 970 participants without depression at baseline were included (mean age 72.5 years, 54.6% females). Physical performance measures included the Short Physical Performance Battery (SPPB), 4m gait speed, five times sit-to-stand test, leg extension and flexion, handgrip strength, and 6-Minute Walking Test (6MWT), categorized in gender-specific tertiles. Depression was classified based on the Geriatric Depression Scale (GDS) and a diagnosis from a geriatric psychiatrist. Area under the curve (AUC) and logistic regression analyses were conducted. Results: At baseline, participants developing depression during follow-up (n = 207) scored significantly worse across all physical performance measures than those who did not develop depression. The AUC and predictive power for each physical performance test was similar for all the tests assessed. In logistic regression analysis, after adjusting for 14 potential confounders, worse physical performance across all tests increased the risk of depression. The lowest tertile of the SPPB were at notable odds of developing depression (OR = 1.79; 95%CI: 1.18-2.71). The association between poor physical performance and depression was typically stronger in women than in men, except for 4m gait speed. Limitations: no gold standard used for depression diagnosis; oxidative stress and inflammatory markers were not included; high rate of missing data at follow-up. Conclusion: Low physical performance appears to be an independent predictor of depression over a 4.4-year follow-up in our sample of elderly people.
机译：背景：体能下降预示着老年人的有害结局。考虑到客观的身体表现和突发事件的数据很少。目的：在一项为期4年的研究中，我们调查了客观的身体表现是否可以预测未抑郁的成年人中的抑郁症。设计：纵向。方法：从最初参加Progetto Veneto Anziani研究的3099位老年患者中，纳入970位基线时无抑郁的参与者（平均年龄72.5岁，女性54.6％）。身体机能指标包括短身体机能电池（SPPB），4m步态速度，五次坐直站立测试，腿部伸展和屈曲，握力和6分钟步行测试（6MWT），按性别分类。根据老年抑郁量表（GDS）和老年精神病医生的诊断对抑郁进行分类。进行曲线下面积（AUC）和逻辑回归分析。结果：基线时，在随访过程中发展为抑郁的参与者（n = 207）在所有物理表现指标中的得分均显着低于未发展为抑郁的参与者。对于所有评估的测试，每个物理性能测试的AUC和预测能力均相似。在逻辑回归分析中，在调整了14个潜在的混杂因素后，所有测试中较差的身体表现都会增加患上抑郁症的风险。 SPPB的最低三分位数是发生抑郁的显着几率（OR = 1.79； 95％CI：1.18-2.71）。除了步态速度为4m以外，女性身体机能差和抑郁之间的关联通常比男性强。局限性：没有用于抑郁症诊断的金标准；不包括氧化应激和炎症标记；后续检查中数据丢失率很高。结论：在我们的老年人样本中，在4.4年的随访中，低体能似乎是抑郁症的独立预测因素。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号